HealthDay reported that a review suggests “combining low doses of several different blood pressure drugs may be better than using a standard dose of just one medication.” Investigators “reviewed 42 studies involving ultra-low doses of multiple medications.” Review co-author Dr. Anthony Rodgers said, “What we found was that four quarter doses [of different medications] gives a lot of benefit with few apparent side effects.” The findings were published in Hypertension.
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The New York Times reported, “Growing evidence suggeststhat the method by which blood sugar is lowered may make a big difference in heart risk” in people with type 2 diabetes [T2D]. What’s more, “it’s becoming clear, researchers say, that there’s far too little evidence on how diabetes drugs affect the heart to make rational evidence-based judgments.” This has now “raised a medical dilemma affecting tens of millions of people with type 2 diabetes – and for the doctors who treat them.”
A new 14-year study of 148,739 women with type 2 diabetes (mean age of 63.3 years) showed an overall 18% reduced breast cancer risk for women who used low-dose aspirin daily compared to those who did not after adjusting for confounders. The authors of the Journal of Women’s Healthstudy reported that a high cumulative dose of aspirin over the 14-year study period reduced breast cancer risk by 47%. A cumulative aspirin dosage of >88,900 mg was associated with a reduced risk of breast cancer in women with type 2 diabetes, though additional studies are necessary to confirm the findings.
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