In 3 clinical trials of overweight individuals on diets with a low glycemic load or with large amounts of fiber and whole grains, elevated fasting blood glucose before treatment indicated successful weight loss and maintenance. The American Journal of Clinical Nutrition analysis included information from the Diet, Obesity, and Genes trial; the OPUS Supermarket intervention trial; and the Nutrient-Gene Interactions in Human Obesity trial. For individuals with prediabetes, consuming vegetables, fruits, and wholegrains was effective for weight loss and could potentially improve diabetes markers. A diet rich in healthy fats from plant sources was most effective for patients with type 2 diabetes.
MedPage Today reported that “newly initiated use of an SGLT2 inhibitor was associated with a roughly twofold greater risk of diabetic ketoacidosis versus new initiation of a DPP4 inhibitor,” investigators found after examining “data on 50,220 patients with type 2 diabetes from the TruvenMarketScan database of commercially insured patients,” all of whom “were started on an SGLT2 inhibitor or DPP4 inhibitor prior to the FDA warning (April 2013-December 2014).” The findings were published in The New England Journal of Medicine.
Higher Uric Acid Levels May Be Linked to Elevated Risk for Development of Nephrolithiasis in Men8/2/2017 Renal & Urology News reported that research suggests “higher serum uric acid level is modestly and independently associated with an elevated risk for development of nephrolithiasis in a dose-dependent manner in apparently healthy men, but not women.” The findings were published online in the American Journal of Kidney Diseases.
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